THE IMPACT OF HYPERTENSION, HYPERCHOLESTEROLEMIA, AND SMOKING HISTORY ON STROKE INCIDENCE AT DR. R. SOEDJONO SELONG REGIONAL HOSPITAL

Dera Ayu Ningsih, M. Sofyan Faridi, Risky Irawan Putra, Sukandriani Utami

Abstract


Stroke is a major cause of morbidity and mortality and remains a public health problem, including in East Lombok Regency. The high incidence of stroke is closely related to modifiable risk factors, such as hypertension, hypercholesterolemia, and smoking habits. The novelty of this study lies in the analysis of stroke risk factors based on patient data from Dr R. Soedjono Selong Regional General Hospital, the main referral hospital in East Lombok, which has been reported only to a limited extent. This study aims to analyse the relationship between hypertension, hypercholesterolemia, and smoking history with stroke incidence at Dr R. Soedjono Selong Regional General Hospital. This study is an observational, analytical, cross-sectional study conducted in October–November 2025 on 84 respondents selected using a purposive sampling technique. Data obtained from medical records and structured interviews were then analysed using the chi-square test. The results showed that stroke incidence was found in 57.1% of respondents. Hypertension and hypercholesterolemia were shown to have a significant relationship with stroke incidence, with p-values of 0.005 and 0.000, respectively (p < 0.05), while smoking history did not show a significant relationship with stroke incidence (p-value = 0.243). The conclusion of this study shows that hypertension and hypercholesterolemia are the main risk factors associated with stroke incidence, so that control of these two factors needs to be a priority in stroke prevention efforts at the health service level.

Keywords


Hypercholesterolemia; Hypertension; Risk factors; Stress; Smoking history; Stroke

Full Text:

PDF

References


Belgamwar A, Sharma R, Mali Y, Agrawal YO, Nakhate KT. Nano revolutions in ischemic stroke: A critical analysis of current options and the potential of nanomedicines in diagnosis and therapeutics. Neuroscience [Internet]. 2024 Dec;562:90–105. Available from: https://linkinghub.elsevier.com/retrieve/pii/S0306452224005335

Lucas-Noll J, Clua-Espuny JL, Lleixà-Fortuño M, Gavaldà-Espelta E, Queralt-Tomas L, Panisello-Tafalla A, et al. The costs associated with stroke care continuum: a systematic review. Health Econ Rev [Internet]. 2023 May 17;13(1):32. Available from: https://healtheconomicsreview.biomedcentral.com/articles/10.1186/s13561-023-00439-6

Awal M, Durahim D, Halimah A, Hasbiah H, Arpanjaman A, Supriatna A, et al. Early diagnosis of stroke risk factors in high school students in Makassar, South Sulawesi, Indonesia. Healthc Low-resource Settings [Internet]. 2024 Oct 14; Available from: https://www.pagepressjournals.org/hls/article/view/11961

Harahap HS, Putri SA, Indrayana Y, Amin H, Mahardika FI. Infarct Diameter for Predicting Cognitive Dysfunction in Ischemic Stroke Survivors in West Nusa Tenggara, Indonesia. Kesmas J Kesehat Masy Nas [Internet]. 2022 May 1;17(2). Available from: https://scholarhub.ui.ac.id/kesmas/vol17/iss2/5

Alkahtani R. Molecular mechanisms underlying some major common risk factors of stroke. Heliyon [Internet]. 2022 Aug;8(8):e10218. Available from: https://linkinghub.elsevier.com/retrieve/pii/S2405844022015067

Alhazzani A, Mahfouz A, Abolyazid A, Awadalla N. Risk Factors of the First-Time Stroke in the Southwest of Saudi Arabia: A Case-Control Study. Brain Sci [Internet]. 2021 Feb 11;11(2):222. Available from: https://www.mdpi.com/2076-3425/11/2/222

Prasad K, Mishra M. Mechanism of Hypercholesterolemia-Induced Atherosclerosis. Rev Cardiovasc Med [Internet]. 2022 Jun 9;23(6). Available from: https://www.imrpress.com/journal/RCM/23/6/10.31083/j.rcm2306212

Lisdiana E. Literature Review: Faktor Risiko yang Dapat Diubah Yang Berhubungan Dengan Kejadian Stroke di Indonesia. J Kesehat Bidkesmas. 2025;16(2):127–39.

Halimatunnisa M, Asmawariza LH, Hadi A, Yulandasari V, Wiksuarini E, Pa’ni DMQ, et al. Faktor Risiko Stroke di Rumah Sakit Umum Daerah Praya Tahun 2022. J Kesehat Qamarul Huda. 2023;11(1):371–81.

Martina SE, Siregar R, Sinaga J, Zefanny GF. Hubungan Hipertensi Dengan Kejadian Stroke Pada Lansia Di Taman Bodhi Asri Medan. JHCN J Heal Cardiovasc Nurs. 2025;5(1):29–47.

Saifullah YY, Rachman ME, Ramlian, Limoa LT, Hamado N. Literature Review: Hubungan Hipertensi dengan Kejadian Stroke Iskemik dan Stroke Hemoragik. Fakumi Med J J Mhs Kedokt. 2024;4(10):695–708.

Martina S evi, Siregar R, Sinaga J, Zefanny GF. Relationship Between Hypertension and Stroke in the Elderly in Taman Bodhi Asri Medan. J Heal Cardiovasc Nurs. 2025;5(1):29–47.

Mohammad A, Yadav I, Lashari UG, Sabra S, Sabra A, Sabra M, et al. Hypertension and Risk of Stroke: A Systematic Review and Meta-Analysis. Cureus [Internet]. 2025 Dec;17(12):e99863. Available from: http://www.ncbi.nlm.nih.gov/pubmed/41573492

Rahayu TG. Analisis Faktor Risiko Terjadinya Stroke Serta Tipe Stroke. Faletehan Heal J. 2023;10(1):48–53.

Wang C, Du Z, Ye N, Shi C, Liu S, Geng D, et al. Hyperlipidemia and hypertension have synergistic interaction on ischemic stroke : insights from a general population survey in China. BMC Cardiovasc Disord. 2022;1–8.

Dywanti LSL, Abdillah S, Sumarny R, Diandy MI. Analisis Faktor Risiko Kejadian Stroke Berulang Pada Pasien Stroke. J Ris Sains dan Teknol. 2026;10(1):20–9.




DOI: https://doi.org/10.37905/ijhsmr.v5i2.37229

Refbacks

  • There are currently no refbacks.


Visitor International Journal Of Health Science & Medical Research