Comparative Studies on Proximate and In Vitro Anti-Inflammatory Activities Turmeric Methanol Extract In Albino Wistar Rats

Waheed Sakariyau Adio, Wahab Salawudeen, Ridwan Olamilekan Adesola, Azeez Soliu Adisa, Chizoba Victory Obunadike

Abstract


All throughout the world, turmeric has attracted the interest of scientists and medical specialists. The goal of this study was to pinpoint turmeric methanol extract's immediate proximate and anti-inflammatory activities. A spectrophotometric approach was used to choose the phytochemical screens (both qualitative and quantitative). The recent approach (standard method) was used to research the anti-inflammatory effects and proximate components of turmeric. The qualitative phytochemical screening revealed a substantial amount of turbid alkaloid (++) but no steroid (-). Phenol (151.34±1.01 mg/100g) had the highest concentration (5.83%), while flavonoid (22.30±0.62 mg/100g) had the lowest (5.83%), according to the quantitative screening. The anti-inflammatory activity of the turmeric methanol extract in the treated groups (150, 300, and 600 mg/kg body weight) and the positive control group demonstrated a valuable value (inhibitory values). Paw thickness was also significantly different (reduced) between the 600 mg/kg and positive control groups promising anti-inflammatory effects. These findings demonstrated that inflammation can be treated using turmeric's anti-inflammatory and adjuvant capabilities.

Keywords


Curcuma longa; Inflammation; Phytochemical

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References


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DOI: https://doi.org/10.37905/jambchem.v6i2.16385

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