Characterization of the manufacturing process simplicia Syzygium aromaticum as raw material for wound healing drug preparations

Naziella Naziella, Wintari Taurina, Mohamad Andrie

Abstract


Characterization is the first step before standardization. Standardization of a drug substance is a requirement to achieve parameters that will ensure constant quality in a preparation. The main compounds contained in clove leaves have analgesic and antibacterial properties to accelerate wound healing. This study aims to characterize the process of making clove leaf simplicia and Simplicia (Syzygium aromaticum) originating from Lemukutan Island, Bengkayang Regency, West Kalimantan as raw material for wound healing drug preparations. Clove leaf Simplicia was characterized biologically including habitat and morphology, physically including organoleptic, microscopic, moisture content, ash content, and acid insoluble ash content, and chemically, namely phytochemical screening. Making clove leaf Simplicia consists of harvesting, wet sorting, washing, drying, dry sorting, packaging, and storage. The yield of clove leaf Simplicia was obtained as much as 70.90%. The results of the characterization of clove leaves showed that the clove tree grows in the highlands, with a tropical climate, with a temperature range of 25 C-32 C. Clove leaves are oval in shape, tapered tip, pinnate leaf bone, leaf length is approximately 9-12 cm and width 4 cm-4.5 cm. The moisture content, ash content, and insoluble ash content of the clove leaf Simplicia powder were 9.21%, 3.05%, and 0.69%, respectively. The outcomes of the phytochemical screening of clove leaf Simplicia powder have beensuperbfor holding flavonoids, saponins, triterpenoids, and tannins.

Keywords


Characterization, Simplicia Clove leaf (Syzygium aromaticum), Phytochemical screening, Medicinal raw materials

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References


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DOI: https://doi.org/10.37311/jsscr.v4i2.14184

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