Formulasi Sabun Mandi Padat Ekstrak Daun Jeruk Bali (Citrus Maxima Merr.) sebagai Antibakteri terhadap Staphyloccous aureus

Noela Riski Riani Sumbung, Vivin Nopiyanti, Siti Aisiyah, Reslely Harjanti

Abstract


Solid bath soap is one of the most common cosmetic preparations used by the public to clean the body from dirt. Grapefruit leaves contain flavonoids that are able to maintain healthy skin, and can inhibit the growth of bacteria. The purpose of this study was to formulate the leaf extract of grapefruit into a solid bath soap that has good physical and stability qualities and to determine its antibacterial effect against S. aureus. Grapefruit leaves were macerated with 96% ethanol solvent then the extract obtained was formulated into solid soap preparations with extract variations, namely 1; 3 and 5%. Furthermore, physical quality and stability tests have been carried out as well as testing the antibacterial activity of the bath soap preparations against S. aureus bacteria by agar diffusion method by means of wells. The final stage was statistical data analysis. The results showed that the solid bath soap preparations with grapefruit leaf extract had good physical quality and stability, the formulation of solid bath preparations with extract concentrations of 1%, 3%, and 5% had antibacterial activity with an average diameter of the inhibition zone against S. aureus bacteria were 5.6 mm, 7 mm and 10.8 mm, respectively, which were included in the moderate to strong category. The formulation with the addition of 5% extract had the most effective antibacterial activity with an average inhibition zone of 10.8 mm.


Keywords


Extract; Grapefruit Leaves; Solid Bath Soap; Staphyloccous aureus

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References


Barel AO, Paye M, Maibach HI, editors. Handbook of cosmetic science and technology. 3rd ed. New York: Informa Healthcare; 2009. 869 p.

Lavenia C, Dyasti JA. Studi Komparatif Personal Hygiene Mahasiswa Universitas Indonesia di Indekos dan Asrama. 2019;1(4).

Anhar LW. FAKULTAS KESEHATAN MASYARAKAT UNIVERSITAS SUMATERA UTARA. 2016;

Duraisamy A. Bioprospecting and new cosmetic product development: A brief review on the current status.

Azizah, N., Jayuska, A., Harlia. (2015). Aktivitas Anti Rayap Ekstrak Daun Jeruk Bali (Citrus Maxima (Burm.) Merr.) Terhadap Rayap Tanah Coptotermes sp. Jurnal Kimia Katulistiwa, 4(3): 33-39

Aiello, S. E. (2012). The Merck Etinary Manual. USA: Merck Sharp & Dohme Corp

Mahardika, Sarwiyono, Surjowardojo. (2013). Ekstrak Metanol Daun Kersen (Muntingia calabura L) Sebagai Antimikroba Alami Terhadap Bakteri Staphylococcus Aureus Penyebab Mastisis Subklinis Pada Sapi Perah. Ternak Tropika, 15(2)

Jawetz, E. Melnick, J. L dan Adelberg, E.A. (2007). Mikrobiologi Kedokteran Edisi 23. Salemba Medika, Jakarta

Mastur, L., Rifqi, M., Kusumawardani, I.M., Harismah, K. (2021). Pembuatan Sabun Padat Antimikroba dari Ekstrak Daun Steva (Stevia Rebaudiana Bertoni) dan biji kopi in Prosiding SNPBS (Seminar Nasional Pendidikan Biologo dan Saintek)

Davis, W.W., & Stout, T.R., (1971). Disc Plate Method of Microbiological Antibiotic Assay. Applied Microbiology, 22 (1): 659-665.

Departemen Kesehatan Republik Indonesia. (2008) Farmakope Herbal Indonesia, Edisi I, Departemen Kesehatan Republik Indonesia, Jakarta, Indonesia

Harborne, J.B. (1987). Metode Fitokimia. Terjemahan: Padmawinata, K., dan Soediro, I. Bandung : Institut Teknologi Bandung

Rahmi, U., Yunazar, M., & Adlis, S. (2013). Profil Fitokimia Metabolit Sekunder dan Uji Aktivitas Antioksidan Tanaman Jeruk Purut (Citrus Histrix DC) dan Jeruk Bali (Citrus Maxima (Burm. F.) Merr). Jurnal Kimia Unand, 2(2): 109-114.

Todar, K. (2002). Todar’s Online Textbook of Bacteriology: Streptococcus pyogenes, Universitas of Wisconsin-Madison Departement of Bacteriology

Dewi, A. K. (2013). Isolasi, identifikasi dan uji sensitivitas Staphylococcus aureus terhadap amoxicillin dari sampel susu kambing peranakan ettawa (PE) penderita mastitis di wilayah Girimulyo, Kulonprogo, Yogyakarta. Jurnal Sain Veteriner, 31(2): 138-150.

Lay, B. W. (1994) Analisis Mikroba di Laboratorium. PT Raja Grafindo Persada. Jakarta.

Boerlin, P., Kuhnert, P., Hussy, D., Schaellibaum, M. (2003). Methods for Identification of Staphylococcus aureus Isolates In Cases of Bovine Mastitis. J. Clin. Microbiol., 41(2): 767-771.

Ote, I., Taminiau, B., Duprez, J.N., Dizier, I. and M a i n i l , J . G . ( 2 0 1 1 ) G e n o t y p i c characterization by Polymerase Chain Reaction of Staphylococcus aureus isolates associated with bovine mastitis. Vet. Microbiol. 153: 285-292.




DOI: https://doi.org/10.37311/jsscr.v5i1.16874

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