_ok_o_ff.png)
1.png)
Formulasi dan Uji Aktivitas Sabun Cair Ekstrak Daun Sirih Merah (Piper crocatum Riuz & Pav.) Terhadap Bakteri Staphylococcus aureus
Abstract
Red betel is one of the efficacious medicinal plants. Based on scientific research, red betel leaves are antibacterial because they contain flavonoids, alkaloids, saponins and tannins. This research aims to make liquid soap preparations as an antiseptic and determine the ability of liquid soap preparations to inhibit the growth of Staphylococcus aureus bacteria. The type of research is laboratory experimental. Red betel leaf ethanol extract liquid soap formulations with concentrations of 2.5%, 5% and 7.5% were tested for irritation, organoleptic, pH, foam height and specific gravity. Tests carried out on Staphylococcus aureus bacteria used the diffusion method. The results of liquid soap quality testing meet the requirements according to the standards set by SNI. The observation results obtained with the average inhibition zone for a concentration of 2.5% were 15.30 mm, 5% was 15.60 mm, 7.5% was 16.86 mm, positive control was 30.86 mm, while the control negative, no inhibition zone is formed. The conclusion of this research is that red betel leaf extract (Piper crocatum Riuz & Pav.) has inhibitory power against Staphylococcus aureus bacteria, namely concentrations of 2.5%, 5% and 7.5% are in the strong category. It is recommended that future researchers test the antibacterial activity of red betel leaf extract against other types of bacteria.
Keywords
Full Text:
PDFReferences
P. J. Puspita, M. Safithri, and N. P. Sugiharti, “Antibacterial Activities of Sirih Merah (Piper crocatum) Leaf Extracts,” Curr. Biochem., vol. 5, no. 3, pp. 1–10, 2019, doi: 10.29244/cb.5.3.1-10.
S. Wijana and T. Harnawi, “The Study on Liquid Soap Production from Recycled Frying Oil ( The Effect of Mixing Time and Water : Soap Ratio on the Quality ) Quality ),” J. Teknol. Pertan., vol. 10, no. 1, pp. 54–61, 2009.
F. J. Rachmawati and S. Y. Triyana, “Perbandingan Angka Kuman Pada Cuci Tangan Dengan Beberapa Bahan Sebagai Standarisasi Kerja di Laboratorium Mikrobiologi Fakultas Kedokteran Universitas Islam Indonesia,” Logika, vol. 58, no. 1, pp. 1–13, 2008, doi: 10.20885/logika.vol5.iss1.art3.
A. Ballal and A. C. Manna, “Expression of the sarA family of genes indifferent strains of Staphylococcus aureus,” Microbiology, vol. 155, no. 7, pp. 2342–2352, 2009, doi: 10.1099/mic.0.027417-0.
J. Reveny, “Daya Antimikroba Ekstrak dan Fraksi Daun Sirih Merah ( Piper betle Linn .) Antimicrobial Activity of the Extract and Fraction of Red Betel Leaf ( Piper betle Linn .),” J. ILMU DASAR, vol. 12, pp. 6–12, 2011.
F. J. Rachmawaty, D. Ayu, C. Mahardina, B. Nirwani, T. Nurmasitoh, and E. T. Bowo, “Manfaat Sirih Merah (Piper crocatum) Sebagai Agen Anti Bakterial Terhadap Bakteri Gram Positif dan Gram Negatif,” J. Kedokt. dan Kesehat. Indones., vol. 1, no. 1, pp. 12–20, 2016, [Online]. Available: https://journal.uii.ac.id/JKKI/article/view/543
A. Rukmini, D. H. Utomo, and A. N. Laily, “Family Piperaceae Phytochemical Screening,” J. Biol. dan Pembelajarannya, vol. 7, no. 1, pp. 28–32, 2020.
S. A. Dimpudus, P. V. Y. Yamlean, and A. Yudistira, “Formulasi Sediaan Sabun Cair Antiseptik Ekstrak Etanol Bunga Pacar Air (Impatiens balsamina L.) dan Uji Efektivitasnya Terhadap Bakteri Staphylococcus aureus Secara In Vitro,” PHARMACON J. Ilm. Farm., vol. 6, no. 3, pp. 208–215, 2017.
M. Rachmawati and H. Dewajani, “Pembuatan Sabun Mandi Cair Dari Minyak Kelapa Sawit Dengan Metode Hot Dan Cold Process,” DISTILAT J. Teknol. Separasi, vol. 8, no. 4, pp. 676–684, 2022, doi: 10.33795/distilat.v8i4.437.
A. Chan, “FORMULASI SEDIAAN SABUN MANDI PADAT DARI EKSTRAK BUAH APEL (Malus domesticus) SEBAGAI SABUN KECANTIKAN KULIT,” J. Ilm. Manuntung, vol. 2, no. 1, pp. 51–55, 2017, doi: 10.51352/jim.v2i1.46.
R. Sari and A. Ferdinan, “Pengujian Aktivitas Antibakteri Sabun Cair dari Ekstrak Kulit Daun Lidah Buaya Antibacterial,” Pharm Sci Res, vol. 4, no. 3, pp. 111–120, 2017.
F. A. Marhaba, P. V. . Yamlean, and K. L. R. Mansauda, “Formulasi Dan Uji Efektivitas Antibakteri Sediaan Sabun Wajah Cair Ekstrak Etanol Buah Pare (Momordica Charantia L.) Terhadap Bakteri Staphylococcus Epidermidis,” Pharmacon, vol. 10, no. 13 mm, p. 1051, 2021.
D. F. Lestari, F. Fatimatuzzahra, and D. Dominica, “Uji Daya Hambat Bakteri Staphylococcus Aureus Sabun Cuci Tangan Cair Berbahan Arang Aktif Batok Kelapa,” J. Sains dan Kesehat., vol. 3, no. 2, pp. 242–247, 2021, doi: 10.25026/jsk.v3i2.384.
D. A. Sumilat, “Skrinning Aktivitas Antibakteri Beberapa Jenis Spons Terhadap Pertumbuhan Strain Bakteri Staphylococcus aureus, Escherichia coli, Staphylococcus saprophyticus, dan Pseudomonas aeruginosa,” J. Ilm. Platax, vol. 7, no. 2, pp. 1689–1699, 2019.
DOI: https://doi.org/10.37311/jsscr.v4i3.25697
Refbacks
- There are currently no refbacks.
Copyright (c) 2024 Journal Syifa Sciences and Clinical Research (JSSCR)
| EDITORIAL OFFICE OF JOURNAL SYIFA SCIENCES AND CLINICAL RESEARCH |
| Department of Pharmacy, Gorontalo State University Jl. Jenderal Sudirman No.6, Kota Gorontalo, Provinsi Gorontalo 96128, Indonesia |
| Email: info.jsscr@ung.ac.id Google Scholar : JOURNAL SYIFA SCIENCES AND CLINICAL RESEARCH |
