Aktivitas Antioksidan Daun Sirsak (Annona muricate L.): A Systematic Review

Rinoa Sahda Rahayu, Cyntia Wulandari

Abstract


Antioxidants are compounds that can ward off free radicals that can affect health. This study aims to identify antioxidant compounds in soursop leaves through a literature review writing method with reference to PRISMA. Which was conducted between 12 and 14 December 2024 online through Dimension with the keywords "soursop leaves"; OR/AND "antioxidants". According to the findings of this review, three journals were identified that discuss the antioxidant activity of soursop leaves (Annona muricata L.) using the DPPH method, as indicated by the IC50 results. There were 3 articles that were included in the selection and the results showed that soursop leaves are used as a source of natural antioxidants that are effective in fighting free radicals.


Keywords


Antioxidants; Soursop leaves; Free radicals; DPPH

Full Text:

PDF

References


Rosalina Y. Kurang and Bepang Adang, “Skrining Fitokimia Dan Uji Aktivitas Antioksidan Daun Sirsak (Annona Muricata L) Dengan Metode 1,1-Difenil-2-Pikrylhidrazyl (Dpph),†Partner, vol. 23, no. 1, p. 567, 2018.

Yahaya Gavamukulya, Faten Abou-Elella, Fred Wamunyokoli, and Hany AEl-Shemy, “Phytochemical screening, anti-oxidant activity and in vitro anticancer potential of ethanolic and water leaves extracts of Annona muricata (Graviola),†Asian Pac J Trop Med, vol. 7, pp. S355–S363, 2014.

A. Werdhasari, “Peran Antioksidan Bagi Kesehatan,†Jurnal Biotek Medisiana Indonesia, vol. 59, p. 68, 2014.

A. Nirmala Sari, “ANTIOKSIDAN ALTERNATIF UNTUK MENANGKAL BAHAYA RADIKAL BEBAS PADA KULIT,†2015. doi: http://dx.doi.org/10.22373/ekw.v1i1.518.

Adri Delvi, Wikanastri Hersoelistyorini, and Agus Suyanto, “Aktivitas Antioksidan dan sifat organoleptik teh daun sirsak (annona muricata Linn.) berdasarkan variasi lama pengeringan,†Jurnal Pangan dan Gizi, vol. 4, no. 1, 2013.

L. Nurdianti, I. Rahmiyani, S. B. Tunas, H. Tasikmalaya, and P. S1-Farmasi, “UJI AKTIVITAS ANTIOKSIDAN KRIM EKSTRAK DAUN MANGGA (Mangifera indica L) Terhadap DPPH (1,1-diphenyl-2-picrylhydrazil),†2016. doi: https://doi.org/10.36465/jkbth.v16i1.165.

J B Minari, “Chemopreventive effect of Annona muricata on DMBA-induced cell proliferation in the breast tissues of female albino mice,†The Egyptian Journal of Medical Human Genetics, vol. 15, no. 4, pp. 327–334, 2014.

A. Gani and R. Delviyanti, “ANTIOXIDANT ACTIVITY TEST ON ETHANOL EXTRACT OF SOURSOP LEAVES (Annona muricata L.) USING DPPH METHOD (1,1-DIPHENYL-2-PICRYLHIDRAZYL),†EduChemia Jurnal Kimia dan Pendidikan, vol. 6, no. 2, 2021, doi: 10.30870/Educhemia.V6i1.10159.

Jackie Kang Sing Lung and Dika Pramita Destiani, “Uji Aktivitas Antioksidan Vitamin A, C, E dengan metode DPPH,†Farmaka, vol. 15, no. 1, pp. 53–62, 2017.

T. Rudiana, D. Danang Indriatmoko, K. Firginia, and U. M. Magelang, “ANTIOXIDANT ACTIVITY OF THE COMBINATION OF AMBARELLA LEAVES (Spondias dulcis Parkinson) AND SOURSOP LEAVES (Annona muricata Linn) EXTRACT,†JFSP, vol. 9, no. 2, pp. 2579–4558, 2023, doi: 10.31603/pharmacy.v9i1.5082.

I. D. K. Kamaluddin, P. T. Ramadhani, I. H. Bima, A. A. Irwan, and R. F. Matoo, “Comparative Analysis of Antioxidants in Moringa Leaves and Soursop Leaves,†Jurnal Biologi Tropis, vol. 24, no. 2, pp. 81–88, May 2024, doi: 10.29303/jbt.v24i2.6760.

Ni Kadek Fina Parwati, Mery Napitupulu, and Anang Wahid M. Diah, “UJI AKTIVITAS ANTIOKSIDAN EKSTRAK DAUN BINAHONG (Anredera Cordifolia (Tenore) Steenis) DENGAN 1,1-DIFENIL-2-PIKRILHIDRAZIL (DPPH) MENGGUNAKAN SPEKTROFOTOMETER UV-VIS,†Jurnal Akademi Kimia, vol. 3, no. 4, pp. 206–213, 2014.

Hassan A. Al-Hmoud, Nasser E. Ibrahim, and Ehab I. El-Hallous, “Surfactants solubility, concentration and the other formulations effects on the drug release rate from a controlled-release matrix.,†Afr J Pharm Pharmacol, vol. 8, no. 13, pp. 364–371, 2014.

Liaudanskas Mindaugas, Pranas Viskelis, Raimondas Raudonis, Darius Kviklys, Norbertas Uselis, and Valdimaras Janulis, “Phenolic Composition and Antioxidant Activity of Malus domestica Leavestioxidant Activity of Malus domestica Leaves,†The Scientific World Journal, pp. 1–10, 2014.

Zerlinda Theafelicia and Siti Narsito Wulan, “PERBANDINGAN BERBAGAI METODE PENGUJIAN AKTIVITAS ANTIOKSIDAN (DPPH, ABTS DAN FRAP) PADA TEH HITAM (Camellia sinensis),†Jurnal Teknologi Pertanian, vol. 24, no. 1, pp. 35–44, 2023.




DOI: https://doi.org/10.37311/jsscr.v7i1.29345

Refbacks

  • There are currently no refbacks.


Copyright (c) 2025 Journal Syifa Sciences and Clinical Research (JSSCR)

EDITORIAL OFFICE OF JOURNAL SYIFA SCIENCES AND CLINICAL RESEARCH
  Department of Pharmacy, Gorontalo State University
Jl. Jenderal Sudirman No.6, Kota Gorontalo, Provinsi Gorontalo 96128, Indonesia
 Email: info.jsscr@ung.ac.id
Google Scholar : JOURNAL SYIFA SCIENCES AND CLINICAL RESEARCH

Creative Commons License

Journal Syifa Sciences and Clinical Research (JSSCR) is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.