Penapisan Fitokima dan Evaluasi Parameter Mutu Spesifik Ekstrak Etanol Bunga Telang (Clitoria ternatea)
Abstract
Butterfly pea flower (Clitoria ternatea) is a medicinal plant rich in secondary metabolites such as flavonoids, triterpenoids, saponins, alkaloids, and phenolic compounds. These bioactive compounds exhibit various pharmacological activities, including antioxidant, neuroprotective, anti-inflammatory, antimicrobial, hypoglycemic, and anticancer properties. This study aims to evaluate the specific and non-specific quality parameters of ethanol extract from Clitoria ternatea. The extract was obtained using ultrasonic-assisted extraction with 70% and 96% ethanol. The quality parameters assessed included soluble compound content, moisture content, residual solvent, microbial contamination, and heavy metal contamination based on the Indonesian Herbal Pharmacopoeia standards. The results indicate that the ethanol extract of Clitoria ternatea meets the required quality standards, demonstrating potential applications in pharmaceutical and cosmetic formulations.
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Departemen Kesehatan RI, Parameter Standar Umum Ekstrak Tanaman Obat, vol. 1. Departemen Kesehatan RI, 2000, pp. 10-11.
Fatimawali, J. B. Kepel, and B. W. Kepel, "Standarisasi parameter spesifik dan nonspesifik ekstrak rimpang lengkuas merah (Alpinia Purpurata K. Schum) sebagai obat antibakteri" J. e-Biomedik, vol. 8, no. 1, pp. 63-67, 2020.
A. Burhan, A. Rahim, and Regina, "Standardisasi parameter spesifik dan non spesifik ekstrak etanol daun kecombrang (Etlingera elatior (Jack) R. M. Smith)" J. Pharm. Med. Sci., vol. 1, no. 2, pp. 21-24, 2016.
T. N. M. Tuan Putra, M. K. Zainol, N. S. Mohdisa, and N. Mohdmaidin, "Chemical characterization of ethanolic extract of butterfly pea flower (Clitoria ternatea)" Food Res., vol. 5, no. 4, pp. 127-134, 2021. [Online]. Available: https://doi.org/10.26656/fr.2017.5(4).634
N. F. Jaafar, M. E. Ramli, and R. M. Salleh, "Optimum extraction condition of Clitoria ternatea flower on antioxidant activities, total phenolic, total flavonoid and total anthocyanin contents" Trop. Life Sci. Res., vol. 31, no. 2, pp. 1-17, 2020.
N. Kamkaen and J. M. Wilkinson, "The antioxidant activity of Clitoria ternatea flower petal extracts and eye gel" J. Pharm. Res., pp. 28-30, 2009.
M. B. Lijon, N. S. Meghla, E. Jahedi, M. A. Rahman, and I. Hossain, "Phytochemistry and pharmacological activities of Clitoria ternatea" Int. J. Nat. Soc. Sci., vol. 4, no. 1, pp. 1-10, 2017.
Kementerian Kesehatan RI, Suplemen I Farmakope Herbal Indonesia Edisi II, Jakarta: Departemen Kesehatan Republik Indonesia, 2022, pp. 1-236.
N. R. Farnsworth, "Biological and phytochemical screening of plants" J. Pharm. Sci., vol. 55, no. 3, pp. 225-276, 1966. [Online]. Available: https://doi.org/10.1002/jps.2600550302
Departemen Kesehatan RI, Materia Medika Indonesia (Jilid V), Jakarta: Departemen Kesehatan Republik Indonesia, 1989.
S. E. Goh, P. J. Kwong, C. L. Ng, W. J. Ng, and K. Y. Ee, "Antioxidant-rich Clitoria ternatea L. flower and its benefits in improving murine reproductive performance" Food Sci. Technol., vol. 2061, pp. 1-7, 2021.
N. Kamkaen and J. M. Wilkinson, "The antioxidant activity of Clitoria ternatea flower petal extracts and eye gel" J. Pharm. Res., pp. 28-30, 2009.
T. N. M. Tuan Putra, M. K. Zainol, N. S. Mohdisa, and N. Mohdmaidin, "Chemical characterization of ethanolic extract of butterfly pea flower (Clitoria ternatea)" Food Res., vol. 5, no. 4, pp. 127-134, 2021. [Online]. Available: https://doi.org/10.26656/fr.2017.5(4).634
K. P. Swathi, S. Jayaram, D. Sugumar, and E. Rymbai, "Evaluation of anti-inflammatory and anti-arthritic property of ethanolic extract of Clitoria ternatea" Chin. Herb. Med., vol. 13, no. 2, pp. 243-249, 2021. [Online]. Available: https://doi.org/10.1016/j.chmed.2021.04.004
N. F. Ramadhani et al., "Clitoria ternatea ethanol extract antibacterial and anti-inflammatory ability towards peri-implantitis biomarkers: An in vitro and in silico study" J. Int. Dent. Med. Res., vol. 16, no. 3, pp. 1038-1049, 2023.
N. F. Jaafar, M. E. Ramli, and R. M. Salleh, "Optimum extraction condition of Clitoria ternatea flower on antioxidant activities, total phenolic, total flavonoid and total anthocyanin contents" Trop. Life Sci. Res., vol. 31, no. 2, pp. 1-17, 2020.
N. Jamil, M. Naqiuddin, M. Zairi, A. Nur, M. Nasim, and F. Pa, "Influences of environmental conditions to phytoconstituents in Clitoria ternatea (Butterfly Pea Flower)" J. Plant Sci., 2019.
E. J. Jeyaraj, "Extraction methods of butterfly pea (Clitoria ternatea) flower and biological activities of its phytochemicals" J. Food Sci. Technol., 2020.
T. N. Pham, T. D. Lam, M. T. Nguyen, and X. T. Le, "Effect of various factors on extraction efficiency of total anthocyanins from Butterfly pea (Clitoria ternatea L. Flowers) in Southern Vietnam" J. Agric. Food Chem., 2019.
BPOM RI, Persyaratan Mutu Obat Tradisional, Peraturan Kepala Badan Pengawas Obat dan Makanan Republik Indonesia, 2014.
DOI: https://doi.org/10.37311/jsscr.v7i1.30316
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