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Conventional Pap Smear Findings Among Gynecological Patients at Siloam Hospital West Jakarta, 2023-2025
Abstract
Introduction: Cervical cancer remains a major global health burden, and cervical screening is essential for detecting precancerous changes before invasive disease develops. This study aimed to describe conventional Pap smear cytology findings among gynecological patients at Siloam Hospital in West Jakarta during 2023-2025.
Method: A retrospective descriptive cross-sectional design was used. Medical records of all eligible female patients who underwent conventional Pap smear examinations during the study period were included through total sampling. Cytology was classified using the Bethesda reporting system and summarized as frequencies and percentages.
Results: A total of 4,178 examinations were analyzed. Negative for intraepithelial lesion or malignancy (NILM) was reported in 3,707 cases (88.73%). The most frequent abnormal category was atypical squamous cells of undetermined significance (ASC-US), with 455 cases (10.89%), followed by low-grade squamous intraepithelial lesion (LSIL) in 8 (0.19%), atypical squamous cells-cannot exclude HSIL (ASC-H) in 5 (0.12%), high-grade squamous intraepithelial lesion (HSIL) in 2 (0.05%), and atypical glandular cells (AGC) in 1 (0.02%). No invasive malignancy was documented.
Conclusion: Most examinations were NILM, while ASC-US accounted for nearly all abnormal cytology. High-grade abnormalities were uncommon. These findings provide a three-year institutional cytology profile that may support evaluation and planning of cervical screening services.
Keywords: Cervical cytology, conventional Pap smear, gynecological patients, screening
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Bray F, Laversanne M, Sung H, Ferlay J, Siegel RL, Soerjomataram I, et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024;74(3):229-263.
World Health Organization. Global strategy to accelerate the elimination of cervical cancer as a public health problem. Geneva: World Health Organization; 2020.
Pangarkar MA. The Bethesda system for reporting cervical cytology. CytoJournal. 2022;19:28.
Wahidin M, Febrianti R, Susanty F, Hasanah SR. Twelve years implementation of cervical and breast cancer screening program in Indonesia. Asian Pac J Cancer Prev. 2022;23(3):829-837.
Setiawan D, Miranti I, Partiwi TD, Puspitasari DA, Ramadhan FN. The willingness for cervical cancer screening among sexually active women in Indonesia: lesson learned from two districts. Int J Gynaecol Obstet. 2022;159(1):145-151.
Hafidz F, Icanervilia AV, Rizal MF, Listiani P, Setyaningsih H, Sasanti ML, et al. Economic evaluation of cervical cancer screening by HPV DNA, VIA, and Pap smear methods in Indonesia. Asian Pac J Cancer Prev. 2024;25(9):3015-3022.
Saleh EE, Jamli MM, Shahbodin DM, Pau E, Periyathamby H, Gobu K, et al. Prevalence of Pap smear among female health personnel in Hospital Tuanku Ja'afar Seremban, Malaysia. Asian Pac J Cancer Care. 2021;6(2):189-196.
Tao X, Austin RM, Yu T, Zhong F, Zhou X, Cong Q, et al. Risk stratification for cervical neoplasia using extended high-risk HPV genotyping in women with ASC-US cytology: a large retrospective study from China. Cancer Cytopathol. 2022;130(4):248–258.
Onwusulu DN, Ilikannu SO, Ochuba CO, Idama V, Egboduku E, Fagbemi AJ, et al. Age and pattern of cervical smear cytology in Federal Medical Centre Asaba: a five year review. Adv Med Pharm Dent Res. 2025;5(1):33–37.
Justa U, Mittal R, Negi K, Rathore S, Sharma S, Choudhary A, et al. Prospective observational study of cervical cancer screening by Pap smear in tertiary care hospital in hilly areas of Himachal Pradesh. Int J Reprod Contracept Obstet Gynecol. 2024;13(11):3229-3233.
Khuraijam SD, Singh YD, Devi KP, Khuraijam S, Choudhurimayum R. Cervical smear screening by Pap smear and surveillance of HPV infection among patients attending gynaecology OPD in a tertiary care center: a 12-months study. Ann Pathol Lab Med. 2025;12(8):A252-A257.
Ucak R, Dilbaz OF, Polat N. Analysis of the differences between Bethesda groups according to conventional smear and liquid-based cytology methods in cervicovaginal cytology: a single-center experience with 165,915 cases. Acta Cytol. 2024;68(1):54-59.
Kldiashvili E, Khuntsaria I, Kekelia E, Mamiseishvili A, Abuladze M. A comparative study of conventional Pap smear and liquid-based cytology. Health Sci Rep. 2025;8(4):e70768.
Andola SK, Andola US, Andola SS, Antony AT, Masgal M, Patil AG, et al. Should liquid-based cytology be preferred than conventional Pap smear: a comparative analysis. J Obstet Gynaecol India. 2024;74(4):311-318.
Pathuthara S, Dighe S, Uke M, Prabhudesai N, Deodhar K, Desai SB. Conventional versus liquid-based cytology: man versus machine. J Cytol. 2023;40(4):169-176.
Bavikar R, Patel N, Buch A, Kulkarni M, Dharwadkar A, Viswanathan V. A comparison of conventional Pap smear and liquid-based cytology for cervical cancer screening. Gynecol Minim Invasive Ther. 2023;12(2):77-82.
Liu Q, Zhou X, Zhang X, Strickland AL, Zheng W, Chen H, et al. HPV genotype specific and age stratified immediate prevalence of cervical precancers and cancers in women with NILM/hrHPV+: a single center retrospective study of 26,228 cases. Cancer Manag Res. 2021;13:6869-6877.
Dillner J, Mühr LSA, Kleppe SN, Wang J, Andersson H, Elfström M, et al. The Swedish cervical screening cohort. Sci Data. 2024;11:697.
Li B, Dong L, Wang C, Li J, Zhao X, Dong M, et al. Analysis of the related factors of atypical squamous cells of undetermined significance (ASC-US) in cervical cytology of post-menopausal women. Front Cell Infect Microbiol. 2023;13:1123260.
Choi MS, Lee YJ, Lee EH, Ji YI, Park MJ. Factors associated with cyto-histological misinterpretation of cervical smear according to menopausal status. J Menopausal Med. 2022;28(2):78-84.
Perkins RB, Guido RS, Castle PE, Chelmow D, Einstein MH, Garcia F, et al. 2019 ASCCP risk-based management consensus guidelines for abnormal cervical cancer screening tests and cancer precursors. J Low Genit Tract Dis. 2020;24(2):102-131.
Perkins RB, Guido RS, Castle PE, Chelmow D, Einstein MH, Garcia F, et al. 2019 ASCCP risk-based management consensus guidelines: updates through 2023. J Low Genit Tract Dis. 2024;28(1):3-6.
DOI: https://doi.org/10.37905/jmhsj.v6i1.41275
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