GARLIC (Allium Sativum) EXTRACT EFFECTIVENESS TEST AGAINST TRICHOPHYTON RUBRUM AND PITYROSPORUM OVALE MUSHROOM
Abstract
Seborrheic dermatitis and dandruff are chronic papulo squama skin disorders. with a predilection for areas rich in sebum glands, scalp, face and body. Tinea corporis itself is a dermatophytosis in area of the body skin that has no hair (glabrous skin). In general, itchy rashes are found on the body, extremities or face. Methods: this type of research is experirnental then the research design uses the disc diffusion method with the Posttest Only Control Group Design. Each treatment for 1 mushroom was repeated 4 times, thus the total sample for 2 mushrooms was 16 samples. The extract concentration was made into 4 concentration, namely 15%, 30%, 45%, 60% and positive control (ketokenazole) then the inhibition test was carried out on both fungi, namely Trychophyton rubrum and Pityrosporum ovale using PDA (Potato Dextrose Agar) media. Results: The research showed that garlic ethanol extract could inhibit fungal growth at concentrations of 15%, 30%, 45%, 60% and positive control (ketokenazole) with an average diameter of the inhibitory zone power test for Trychophyton rubrum 6.85mm, 7.00mm. , 7.50mm, 8.35mm, and 12.30mm. And for the power test the inhibition zones of Pityrosporum ovale were 6.50mm, 11.50mm,12.40mm,15.00mm, and 20.50mm. Conclusion: The conclusion of this study shows that garlic extract has the power to slow down the growth of the fungi Trychophyton rubrum and Pityrosporum ovale in concentrate 60% is 15,00mm and 8,35mm.
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Adhi D, Aida SSD, Aryani S Et Al. Ilmu Penyakit Kulit Dan Kelamin. 2018.
Neo AG, Pérez A, López C, Castedo L, Tojo G. PANDUAN PRAKTIK KLINIS PERDOSKI. Journal Of Organic Chemistry. 2017.
Silvia E, Anggunan A, Effendi A, Nurfaridza I. Hubungan Antara Jenis Kelamin Dengan Angka Kejadian Dermatitis Seboroik. J Ilm Kesehat Sandi Husada. 2020;
Sugita T, Boekhout T, Velegraki A, Guillot J, Hadina S, Cabañes FJ. Epidemiology Of Malassezia-Related Skin Diseases. In: Malassezia And The Skin: Science And Clinical Practice. 2010.
Adhi D, Aida SSD, Aryani S, Benny WE, Detty KD, Emmy DSS, Et Al. Ilmu Penyakit Kulit Dan Kelamin. Fkui. 2018.
Oktaviana N, Kawilarang AP, - D. Patient Profile Of Tinea Corporis In Dr. Soetomo General Hospital, Surabaya From 2014 To 2015. J Berk Epidemiol. 2018;
Hernawan UE, Setyawan AD. Senyawa Organosulfur Bawang Putih ( Allium Sativum L .) Dan Aktivitas Biologinya Aktivitas Biologinya. Biofarmasi. 2014;
Aulia Anwar P, Napiah Nasution A, Wahyuni Nasution S, Lestari Ramadhani Nasution S, Muchti Kurniawan H, Girsang E, Et Al. Uji Efektivitas Ekstrak Daun Sirih Hijau (Piper Betle L) Terhadap Pertumbuhan Jamur Pityrosporum Ovale Pada Ketombe. Ketombe Jurnal Farmacia. 2019.
Diana K. Uji Aktivitas Antijamur Infusa Umbi Bawang Putih (Allium Sativum L.) Terhadap Candida Albicans Serta Profil Kromatografinya. J Farm Galen (Galenika J Pharmacy). 2016;
Aryani, I. A., Argentina, F., Diba, S., Darmawan, H., & Garfendo G. Isolasi Dan Identifikasi Spesies Dermatofita Penyebab Tinea Kruris Di Pusat Pelayanan Kesehatan Primer. J Kedokt Dan Kesehat Publ Ilm Fak Kedokt Univ Sriwijaya, 7(1). 2020;
Irwan I, Akuba M. Uji Efektifitas Kombinasi Perasan Jeruk Nipis Dan Mentimun. Jambura J Heal Sci Res. 2019;1(2):71–8.
Surjowardojo P, Susilorini T, Benarivo V. Daya Hambat Dekok Kulit Apel Manalagi (Malus Sylvestris Mill) Terhadap Pertumbuhan Escherichia Coli Dan Streptococcus Agalactiae Penyebab Mastitis Pada Sapi Perah. Ternak Trop J Trop Anim Prod. 2016;
Putih B. “Sebagai Anti Jamur Terhadap Jamur Pityrosporum Ovale Dan Bahan Baku.” (Mmi). 2009.
Firdaus, I., & Sudiarti D. Efektivitas Perasan Daun Ageratum Conyzoides L. Terhadap Pertumbuhan Jamur Trichophyton Rubrum. Bioshell, 7(1). 2018;
DOI: https://doi.org/10.35971/jjhsr.v4i3.12199
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