Pengaruh Ekstrak Etanol Buah Tengkawang Tungkul (Shorea stenoptera Burck) Terhadap Perilaku dan Indeks Organ Tikus Malnutrisi

Inarah Fajriaty, Siti Nani Nurbaeti, Hariyanto IH, Hadi Kurniawan, Fajar Nugraha, Rizki Kurnia Agus Putra

Abstract


Malnutrition is characterized by slow growth and excessive loss of body fat. The fats needed during the growth period of toddlers are essential fatty acids, which are important for the human body and cannot be made in the body but must come from food. specifically omega-3, which is beneficial for children's growth and brain intelligence. The plant that contains this content is the tengkawang fruit. The aim of this study was to examine the effect of tengkawang fruit on motor behavior and organ indices in malnourished male white rats (Rattus norvegicus L.) of the Wistar strain. Research methods include making low-protein animal feed, making test preparations, and grouping animals. Mice were divided into 5 groups, namely positive control, negative control, normal control, and two dose groups; then behavioral observations and organ index observations were observed. The organs observed were the spleen, heart, lungs, liver, and kidneys. The results of behavioral observations in the tengkawang fruit extract group showed that the platform observation increased again after being given the test preparation like the normal group, and the same as motor activity, there was an increase back to normal conditions, especially in the tengkawang fruit extract group at a dose of 100 mg/kgBB, where there was an increase exceeding the normal group by 40%. Observation of organ indices did not show a significant increase (p > 0.05) in the lymph organs, heart, lungs, liver, and kidneys compared to the normal group. Giving tengkawang fruit extract at a dose of 100 mg/kgBB and a dose of 300 mg/kgBB can make the behavior and organ index of malnourished mice return to normal. However, it did not show a significant increase (p > 0.05) between the two dose groups and the negative control group, so it is recommended that further research be carried out using an inert solvent with tengkawang tungul extract.

Keywords


Malnutrition; Extract Tengkawang Tungkul fruit; Behavior; Organ Index

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DOI: https://doi.org/10.37311/ijpe.v4i1.24810

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