Artikel Review: Aktivitas Daun Benalu (Dendrophthoe pentandra (L.) Miq) Sebagai Antioksidan dengan metode DPPH (2,2-Diphenyl-1-Picrylhydrazyl)

Anak Agung Sagung Sri Prabandari, Ni Nyoman Wahyu Udayani, Ginza Afriyanchika Putri Triyansyah, Ni Putu Eka Mahita Kumari Dewi, Ida Ayu Putu Widiasriani, Ni Luh Wayan Eva Wulandari

Abstract


Dendrophthoe pentandra (L.) Miq. or benalu leaf is a variety of hemiparasitic plants used in traditional medicine. The active compounds of benalu leaves include flavonoids, tannins, alkaloids, and saponins. Flavonoids are known to have high antioxidant content. Antioxidants play an active role in warding off free radicals that cause degenerative diseases. The preparation of this review article aims to provide a general identification of the antioxidant activity of benalu leaves with an in vitro model, namely DPPH. The preparation of this review article, obtained by electronic based Google method on the site (Google Scholar, Pubmed, NCBI). After conducting research using the DPPH technique in the in vitro testing model, the IC50 value of benalu leaves was <200 µg/mL. Benalu leaf has a high antioxidant capacity with secondary metabolite compounds contained in it very high, so it can treat various chronic diseases.

Keywords


Free radicals; Antioxidants; Benalu leaf; DPPH

Full Text:

PDF

References


S. Anliza And H. Hamtini, “Uji Aktivitas Antioksidan Ekstrak Metanol Dari Daun Alocasia Macrorrhizos Dengan Metode Dpph,†J. Med. (Media Inf. Kesehatan), Vol. 4, No. 1, Pp. 101–106, 2017, Doi: 10.36743/Medikes.V4i1.75.

K. Ngibad, “Aktivitas Antioksidan, Kadar Fenolik, Dan Kadar Flavonoid Total Daun Jati Cina (Senna Alexandrina),†Lantanida J., Vol. 11, No. 1, P. 24, 2023, Doi: 10.22373/Lj.V11i1.17426.

A. Capacity, O. F. Gula, P. Variant, And O. F. Salak, “Kapasitas Antioksidan Ekstrak Buah Salak (Salacca Zalacca (Gaertn.) Voss) Varian Gula Pasir Menggunakan Metode Penangkapan Radikal Dpph,†Pharmacy, Vol. 13, No. 01, Pp. 116–126, 2016.

G. Pizzino Et Al., “Oxidative Stress: Harms And Benefits For Human Health,†Oxid. Med. Cell. Longev., Vol. 2017, 2017, Doi: 10.1155/2017/8416763.

M. Inggrid And H. Santoso, “Ekstraksi Antioksidan Dan Senyawa Aktif Dari Buah Kiwi ( Actinidia Deliciosa ),†Lemb. Penelit. Dan Pengabdi. Kpd. Masy., Vol. Iii, No. 3, P. 43, 2014.

I. G. Panova And A. S. Tatikolov, “Endogenous And Exogenous Antioxidants As Agents Preventing The Negative Effects Of Contrast Media (Contrast-Induced Nephropathy),†Pharmaceuticals, Vol. 16, No. 8, 2023, Doi: 10.3390/Ph16081077.

B. Poljsak, V. KovaÄ, And I. Milisav, “Antioxidants, Food Processing And Health,†Antioxidants, Vol. 10, No. 3, Pp. 1–11, 2021, Doi: 10.3390/Antiox10030433.

W. Susmayanti And A. Rahmadani, “Antioxidant Activity Of Fraction From Gnetum Gnenom L.Leaves Using Cuprac (Cupric Ion Reduxing Antioxidant Capacity) Methods,†Indones. J. Pharm. Nat. Prod., Vol. 06, No. 01, Pp. 50–55, 2021.

J. M. Al-Khayri Et Al., “Plant Secondary Metabolites: The Weapons For Biotic Stress Management,†Metabolites, Vol. 13, No. 6, Pp. 1–37, 2023, Doi: 10.3390/Metabo13060716.

P. W. K. Hutabarat, R. N. Zulkarnaen, And M. Mulyani, “Keanekaragaman Benalu Di Ecopark, Cibinong Science Center-Botanic Gardens,†Al-Kauniyah J. Biol., Vol. 13, No. 2, Pp. 263–277, 2020, Doi: 10.15408/Kauniyah.V13i2.15112.

K. I. Syahruromadhon, Roy Candra Nainggolan, Zulianti, “Jurnal Teknologi , Kesehatan Dan Ilmu Sosial,†J. Teknol. Kesehat. Dan Ilmu Sos., Vol. 4, No. 2, Pp. 328–338, 2022.

Y. Paula Ranti, “Biofarmasetikal Tropis Biofarmasetikal Tropis,†Trop. J. Biopharm., Vol. 2, No. 2, Pp. 158–169, 2021.

Z. Theafelicia And S. Narsito Wulan, “Perbandingan Berbagai Metode Pengujian Aktivitas Antioksidan (Dpph, Abts Dan Frap) Pada Teh Hitam (Camellia Sinensis),†J. Teknol. Pertan., Vol. 24, No. 1, Pp. 35–44, 2023, Doi: 10.21776/Ub.Jtp.2023.024.01.4.

İ. Gulcin And S. H. Alwasel, “Dpph Radical Scavenging Assay,†Processes, Vol. 11, No. 8, 2023, Doi: 10.3390/Pr11082248.

Y. C. Rini, F. Susilowati, And A. S. S. Amal, “Uji Aktivitas Antioksidan Ekstrak Etanol Dan Ekstrak Air Biji Habbatussauda’ (Nigella Sativa),†Pharm. J. Islam. Pharm., Vol. 4, No. 1, 2020, Doi: 10.21111/Pharmasipha.V4i1.3945.

J. Komunitas And F. Nasional, “Antioxidant Activity In Instant Powders Of Mixed,†Vol. 3, Pp. 602–608, 2023.

I. G. Munteanu And C. Apetrei, “Analytical Methods Used In Determining Antioxidant Activity: A Review,†Int. J. Mol. Sci., Vol. 22, No. 7, 2021, Doi: 10.3390/Ijms22073380.

R. Aryanti, F. Perdana, And R. A. M. R. Syamsudin, “Telaah Metode Pengujian Aktivitas Antioksidan Pada Teh Hijau (Camellia Sinensis (L.) Kuntze),†J. Surya Med., Vol. 7, No. 1, Pp. 15–24, 2021, Doi: 10.33084/Jsm.V7i1.2024.

I. Maitulung, W. Maarisit, D. N. Pareta, And Y. K. Lengkey, “Uji Aktivitas Antioksidan Ekstrak Etanol Akar Manukan (Rhinacanthus Nasutus (L) Kurz),†Trop. J. Biopharm., Vol. 5, No. 2, Pp. 127–134, 2022.

M. Yulian And S. Safrijal, “Uji Aktivitas Antioksidan Daun Benalu Kopi (Loranthus Ferrugineus Roxb.) Dengan Metode Dpph (1,1 – Difenil -2- Pikrilhidrazil),†Lantanida J., Vol. 6, No. 2, P. 192, 2019, Doi: 10.22373/Lj.V6i2.4127.

H. B. Sembiring, S. Lenny, And L. Marpaung, “Aktivitas Antioksidan Senyawa Flavonoida Dari Daun Benalu Kakao (Dendrophthoe Pentandra (L.) Miq.),†Chim. Nat. Acta, Vol. 4, No. 3, P. 117, 2016, Doi: 10.24198/Cna.V4.N3.10920.

F. Palit, G. Tiwon, W. Maarisit, E. Karundeng, And F. Karauwan, “Studi Aktivitas Antioksidan Dan Antikanker Payudara (Mcf-7) Ekstrak Etanol Daun Benalu Langsat Dendrophthoe Pentandra,†Trop. J. Biopharm., Vol. 1, No. 1, Pp. 1–4, 2018.

N. N. W. Udayani, P. D. S. Wiguna, E. Cahyaningsih, And I. G. A. A. K. Wardani, “Skrining Fitokimia Dan Aktivitas Antioksidan Ekstrak Daun Benalu Jeruk (Dendrophthoe Glabrescens (Blakely) Barlow) Dengan Pelarut N-Heksan Dan Etanol,†J. Ilm. Medicam., Vol. 9, No. 2, Pp. 150–157, 2023, Doi: 10.36733/Medicamento.V9i2.7136.

I. A. Telaumbanua And E. B. E. Kristiani, “Kadar Klorofil, Karotenoid, Dan Aktivitas Antioksidan Ekstrak Etanol Daun Dari Dua Jenis Benalu Pada Tanaman Jambu Air (Syzygium Aqueum),†Pros. Semin. Nas. Mipa Unipa, Vol. 2022, Pp. 55–61, 2022, Doi: 10.30862/Psnmu.V7i1.8.

F. Lestari, M. T. Kuswanto, And L. Mulqie, “Perbandingan Ekstrak Benalu Teh (Scurrula Atropurpurea (Bl.) Dans.) Dengan Ekstrak Temulawak (Curcuma Xanthorrhiza) Sebagai Hepatoprotektor Pada Tikus Wistar,†J. Ilm. Farm. Farmasyifa, Vol. 6, No. 1, Pp. 93–99, 2023, Doi: 10.29313/Jiff.V6i1.10816.

N. Kadek, A. Widyantari, N. Putu, M. Ayuk, And D. Gede, “Uji Aktivitas Antioksidan Ekstrak Etanol Daun Benalu Jeruk ( Dendrophthoe Glabrescens ( Blakely ) Barlow ) Dengan Metode Dpph ( 2 , 2- Diphenyl-1-Picrylhydrazyl ),†Vol. 4, No. 1, Pp. 158–167, 2024, Doi: 10.37311/Ijpe.V4i1.25409.

P. (Riset) D. P. Simanjuntak M.Sc., A. S. Kamal, N. Waruwu, B. Bustanussalam, And L. Helawati, “Potensi Multiherbal Daun Benalu Teh (Scurrula Oortiana), Batang Pasak Bumi (Eurycoma Longifolia Jack) Dan Batang Pulai (Alstonia Scholaris) Sebagai Antioksidan,†War. Ind. Has. Pertan., Vol. 39, No. 1, P. 16, 2022, Doi: 10.32765/Wartaihp.V39i1.6947.

R. Helmidanora, H. Nurhasnawati, Y. Sukawaty, A. Priyoherianto, And E. Purwati, “Penentuan Aktivitas Tabir Surya Dan Antioksidan Ekstrak Etanol Benalu (Henslowia Frutescens) Inang Jeruk Bali Secara In Vitro,†J. Ilm. Ibnu Sina Ilmu Farm. Dan Kesehat., Vol. 6, No. 1, Pp. 124–132, 2021, Doi: 10.36387/Jiis.V6i1.647.

A. C. Caritá, B. Fonseca-Santos, J. D. Shultz, B. Michniak-Kohn, M. Chorilli, And G. R. Leonardi, “Vitamin C: One Compound, Several Uses. Advances For Delivery, Efficiency And Stability,†Nanomedicine Nanotechnology, Biol. Med., Vol. 24, No. Xxxx, P. 102117, 2020, Doi: 10.1016/J.Nano.2019.102117.

P. Bunpo, A. Chatarurk, K. Intawong, K. Naosuk, And P. Klangsinsirikul, “Effects Of Ascorbic Acid Supplementation On Immune Status In Healthy Women Following A Single Bout Of Exercise,†Sport Sci. Health, Vol. 17, No. 3, Pp. 635–645, 2021, Doi: 10.1007/S11332-020-00726-3.

S. Hidayati And A. Masykuroh, “Uji Aktivitas Antioksidan Ekstrak Etanol Bunga Pulutan (Urena Lobata L.) Menggunakan Metode Dpph,†J. Komunitas Farm. Nas., Vol. 3, No. 1, Pp. 494–508, 2023.

N. V. Wendersteyt, D. S. Wewengkang, And S. S. Abdullah, “Uji Aktivitas Antimikroba Dari Ekstrak Dan Fraksi Ascidian Herdmania Momus Dari Perairan Pulau Bangka Likupang Terhadap Pertumbuhan Mikroba Staphylococcus Aureus, Salmonella Typhimurium Dan Candida Albicans,†Pharmacon, Vol. 10, No. 1, P. 706, 2021, Doi: 10.35799/Pha.10.2021.32758.

H. M. Amini, I. Tivani, And J. Santoso, “Pengaruh Perbedaan Pelarut Ekstraksi Daun Pandan Wangi (Pandanus Amaryllifolius Roxb) Terhadap Aktivitas Antibakteri Staphylococus Aures,†Diii Farm. Politek. Harapan Bersama, No. 9, Pp. 1–9, 2019.




DOI: https://doi.org/10.37311/ijpe.v4i2.26638

Refbacks

  • There are currently no refbacks.


Copyright (c) 2024 Ni Nyoman Wahyu Udayani

Creative Commons License
Indonesian Journal of Pharmaceutical Education is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.