Kombinasi Krim Ekstrak Daun Pare (Momordica charantia L) dan Kulit Buah Naga Merah (Hylocereus pholyrhizus) sebagai Penyembuhan Luka Bakar

Ni Nyoman Wahyu Udayani, Puguh Santoso, Ni Ketut Putri Aprilia Jayanti

Abstract


Burns occur due to damage to the skin caused by various mechanical sources such as chemicals, electricity, heat, sunlight and even nuclear radiation. Healing burns can be done by utilizing existing plants in Indonesia, namely bitter gourd leaves and red dragon fruit skin. Bitter gourd leaves and red dragon fruit skin contain flavonoid compounds that can heal burns. This study aims to determine the healing activity of second degree burns on the back skin of male white rats from cream preparations of bitter gourd leaf extract and red dragon fruit skin. This research is an experimental laboratory. The test used 20 rats which were divided into 5 groups, all rats were burnt and given treatment once a day. The measurement of the diameter of the burned area was carried out every three days for 14 days. The physical quality of the cream was tested which included the organoleptic test, homogeneity test, pH test, spreadability test, and stickiness test. The results of the measurement data were tested statistically, showing that the combination of bitter melon leaf extract cream and red dragon fruit skin with different percentages, namely F1 was 5%:7.5%, F2 was 7.5%:10%, and F3 was 10%.: 15% has burn healing activity. Based on the results of research that has been done, a combination of bitter melon leaf extract cream and red dragon fruit peel with a ratio of 7.5%: 10% has been effective in healing second degree burns.

Keywords


Activity Test; Bitter Melon; Red Dragon Fruit Peel; Cream; Burns

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References


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DOI: https://doi.org/10.37311/ijpe.v4i2.26880

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