PREVALENCE OF COAGULOPATHY IN COVID-19 PATIENTS HOSPITALIZED AT ROYAL PRIMA HOSPITAL

Rika Yohana Manurung, Ainun Fhadilah, Erwin Sopacua

Abstract


 

Infeksi virus Covid-19 berpotensi menyebabkan terjadinya hiperinflamasi sistemik dan badai sitokin yang mengakibatkan koagulopati. Kebaruan penelitian ini mengetahui prevalensi koagulapati pasien Covid-19 yang di rawat inap. Penelitian ini bertujuan untuk mengetahui gambaran persentase koagulopati yang dialami oleh pasien Covid-19 sebagai bahan perbandingan dalam menentukan kasus berat dan peningkatan mortalitas di RS Royal Prima pada tanggal 1 Juni – 31 Agustus 2021. Penelitian ini adalah penelitian deskriptif retrospektif yang dilakukan pada Rumah Sakit Royal Prima Medan selama Juni – Agustus 2021. Penelitian ini melibatkan 91 sampel yang dipilih melalui purposive sampling yang mencakup kriteria inklusi: 1) Rekam medik pasien lengkap, 2) PCR positif, 3) Usia > 18 tahun, dan 4) Pasien dengan koagulopati pada pasien Covid-19. Instrumen yang digunakan dalam penelitian ini adalah data rekam medis dan buku catatan untuk mencatat hasil yang didapatkan dari rekam medis. Hasil penelitian ini menunjukkan bahwa mayoritas pasien yang terdiagnosis Covid-19 di RS Royal Prima didominasi oleh pasien yang termasuk kategori usia manula >65 tahun yaitu sebanyak 23 orang (25,3%), pasien berjenis kelamin perempuan yaitu sebanyak 57 orang (62,6%), serta pasien dengan koagulopati tidak normal yaitu sebanyak 55 orang (60,4%). Kesimpulan mayoritas pasien yang terdiagnosis Covid-19 di RS Royal Prima pada tanggal 1 Juni – 31 Agustus 2021 didominasi oleh pasien yang termasuk kategori usia manula >65 tahun yaitu sebanyak 23 orang (25,3%), pasien berjenis kelamin perempuan yaitu sebanyak 57 orang (62,6%), serta pasien dengan koagulopati tidak normal yaitu sebanyak 55 orang (60,4%).

Kata kunci: Covid-19;  Koagulopati; Prevalensi.

 

 Abstract

Covid-19 virus infection has the potential to cause systemic hyperinflammation and cytokine storms resulting in coagulopathy. The novelty of this study knows the prevalence of coagulapathy of Covid-19 patients who are hospitalized. This study aims to determine the percentage of coagulopathy experienced by Covid-19 patients as a comparison material in determining severe cases and increasing mortality at Royal Prima Hospital on June 1 – August 31, 2021. This research is a retrospective descriptive study conducted at the Royal Prima Hospital Medan during June – August 2021. This study involved 91 samples selected through purposive sampling which included inclusion criteria: 1) Complete patient medical record, 2) positive PCR, 3) Age > 18 years, and 4) Patients with coagulopathy in Covid-19 patients. The instruments used in this study were medical record data and notebooks to record the results obtained from medical records. The results of this study showed that the majority of patients diagnosed with Covid-19 at Royal Prima Hospital were dominated by patients who belonged to the elderly age category >65 years, namely 23 people (25.3%), female patients who were 57 people (62.6%), and patients with abnormal coagulopathy were 55 people (60.4%). The conclusion is that the majority of patients diagnosed with Covid-19 at Royal Prima Hospital on June 1 - August 31, 2021 are dominated by patients who belong to the elderly age category >65 years, namely 23 people (25.3%), female patients who are 57 people (62.6%), and patients with abnormal coagulopathy, namely 55 people (60.4%).


Keywords


Covid-19; Coagulopathy; Prevalence.

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References


Choirul S, Astuti D, Gorontalo PK. Impact Of Covid-19 On Male Fertility. Jambura J Heal Sci Res. 2022;4(3):837–48.

Karantina IM, Sabili A, Deneira CM, Utomo BS. ADHERENCE OF COVID-19 PATIENT ACTIVITY DURING SELF-. Gorontalo J Heal Sci Community. 2022;6(3).

Willim HA, Supit H, Handriyani. Koagulopati pada Coronavirus Disease-2019 (COVID-19): Tinjauan pustaka. Intisari Sains Medis. 2020;Vol. 11, N.

J. H Khizroeya, A. D Makatsariya, Bitzade VO, M.V Tretyakorya, E. V Slukhanchuk, I. Elalamy. Laboratory monitoring of COVID-19 patients and the Significance of Coagulopathy Markers. Obs Gynecol Reprod. 2020;Vol. 14, N.

H. Fogarty, L. Townsend, C. N. Cheallaigh, C. Bergin, I. Martin-Loeches, P. Browne. More on COVID-19 coagulopathy in Caucasian patients. Br J Haematol. 2020;186,.

I. Hamming, W. Timens, M. L. Bulthuis, A. T. Lely, G. Navis, H. Goor. Tissue distribution of ACE2 Protein, the Functional Receptor for SARS Coronavirus. A first Step in Understanding SARS Pathogenesis. J Pathol. 2004;203,:631–637, 2004.

O T. Large-vessel stroke as a presenting feature of Covid-19 in the young. New Engl J Med. 2020;doi: 10.10.

Amalia L, Mokodompis Y. Epidemiological Analysis Of Covid-19 Cases In Gorontalo City ( Case Study Of Kota Tengah International Journal of Health Science & Medical Research. Int J Heal Sci Med Res. 2023;2(1).

J H, Y W. The Clinical Characteristics and Risk Factors of Severe Covid-19. Gerontology. 2021;67:pp 255-66.

R. Khaerunnisa, N.A Rumana, N. Aulia, P. Fannya. Gambaran Karakteristik Pasien Covid-19 di Rumah Sakit Mekar Sari Bekasi Tahun 2020-2021. J Manaj Inf Kesehat Indones. 2022;Vol. 10, N.

W.R Hidayani. Faktor-faktor Risiko yang Berhubungan dengan Covid-19: Literature Review. J untuk Masy Sehat. 2020;vol 4 no 2(pp 120-134).

S. Tian, N. Hu, J. Lou, K. Chen, X. Kang, Z. Xiang. Characteristics of Covid-19 Infection in Beijing. J Infect. 2020;80, n(pp 401-6).

F. Zheng, W. Tang, H. Li YH, Y. L. Xie, Z.G Zhou. Characteristics of Covid-19 Infection in Beijing. Eur Rev Med Pharmacol Sci. 2020;vol 24 no(pp 3304-3410).

MJ A, N M, Z G. Hubungan Umur Dan Jenis Kelamin dengan Stress Kerja Pada Perawat Di Ruang Rawat Inap RSUD Kwaingga Kabupaten Keerom. J Ilmu Sos dan Pendidik. 2021;5, no:477–83.

Y WT, J.E Schimtz, D.H Persing, C. W Stratton. Laboratory diagnosis of COVID-19: current issues and challenges. J Clin Microbiol. 2020;58, n(pp 1-9).

W.D G. Pemeriksaan Diagnosis Laboratorium COVID-19: Keterbatasan dan Tantangannya Saat Ini. J Kedokt Meditek. 2021;Vol. 27 No(pp 173-82).

C. Tanaka, K. Wiargitha, N. Golden. Early Coagulopathy as Risk Factor of Mortality in Abdominal Trauma Patients in Sanglah General Hospital period 2015-2016. Medicina (B Aires). 2018;Vol 49(No 3):382–7.

M. Levi, J. Thachil, T. Iba, Levy JH. Coagulation abnormalities and thrombosis in patients with COVID-19. Lancet Haematol. 2020;7(1):43–50.

H.N Pinto, D.W Fitrina, D. Mirzati. Hiperkoagulopati pada Covid-19. J Hum Care. 2022;vol 7(no 1):43–50.

B.M Henry, J. Vikse, S. Benoit, E.J. Favoloro, G. Lippi. Hyperinflammation and Dearangement of Reninangiotensin-aldosterone System in Covid-19: A Novel hypothesis for Clinically Suspected Hypercoagulopathy and Microvascular Immunothrombosis. Clin Chim Acta. 2020;507:pp 167-73.




DOI: https://doi.org/10.35971/jjhsr.v5i1.16757

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