Mathematical Model of COVID-19 with the Influence of Vaccination

Ndaru Atmi Purnami, Luqman Nuradi Prawadika, Irvandi Gorby Pasangka, Findasari Findasari, Eka Kusumawati, Ilham Yoga Pratama, Ridho Suharis, Nadhira Hasna Maturbongs

Abstract


The COVID-19 pandemic, which first emerged at the end of 2019, has had a significant impact on people's lives around the world. In Indonesia, the outbreak began to develop in February 2020. Although the pandemic has now passed and people have started to resume their normal activities, some individuals are still being infected with COVID-19, even though the number of cases is now under control. One of the key factors in controlling COVID-19 is vaccination. The extent to which vaccination affects COVID-19 transmission will be discussed in this study. Furthermore, a numerical simulation will be conducted on this mathematical model to observe the impact of vaccination on COVID-19. The mathematical model of COVID-19 with vaccination influence will describe the interaction between six population classes, namely: the class of susceptible individuals who can be infected (Susceptible – S), the class of exposed individuals (Exposed – E), the class of vaccinated individuals who have never been infected (Vaccinated – V), the class of infected individuals (Infected – I), the class of individuals who have recovered (Recovered – R), and the class of infected individuals who have died (Death – D). It is important to note that COVID-19 is a disease caused by infection with the coronavirus. A person who has not yet been infected with the virus has the potential to be exposed. One way to prevent exposure is through vaccination. In Indonesia, vaccination has been made mandatory three times: the first dose, the second dose, and the booster. However, because the coronavirus has an incubation period, there is no guarantee that a vaccinated person has not already been exposed to the virus. Exposed individuals will become infected with COVID-19 once the incubation period ends. Infected individuals may show symptoms or be asymptomatic. An infected individual has two possible outcomes: recovery or death. The modeling is based on the SEVIRD model, with its parameters estimated using data. This study produces a mathematical model of COVID-19 with vaccination influence, showing that vaccination plays a role in controlling the spread of COVID-19.

Keywords


COVID-19; SEVIRD; Coronavirus; Vaccination; Mathematical Modeling.

Full Text:

PDF

References


B. K. Umri, E. Utami, and M. P. Kurniawan, “menggunakan Convolutional Neural Networks Systematic Literature Review of Detection Covid-19 using Convolutional Nerual Networks,” Citec J., vol. 8, no. 1, 2021.

S. Nurhalimah, “Covid-19 dan Hak Masyarakat atas Kesehatan,” SALAM J. Sos. dan Budaya Syar-i, vol. 7, no. 6, pp. 543–554, 2020, doi: 10.15408/sjsbs.v7i6.15324.

T. Usherwood, Z. LaJoie, and V. Srivastava, “A model and predictions for COVID-19 considering population behavior and vaccination,” Sci. Rep., vol. 11, no. 1, pp. 1–11, 2021, doi: 10.1038/s41598-021-91514-7.

F. Adi-kusumo and N. Susyanto, “Model Berbasis Sir Dalam Prediksi Awal Penyebaran Covid-19 Di Daerah Istimewa Yogyakarta (Diy) (Sir-Based Model in Predicting the Early Outbreak of Covid-19 in the Special Region of Yogyakarta (Diy)),” J. Mat. Thales, vol. 1, pp. 1–9, 2020.

D. K. Bagal, A. Rath, A. Barua, and D. Patnaik, “Estimating the parameters of susceptible-infected-recovered model of COVID-19 cases in India during lockdown periods,” Chaos, Solitons & Fractals, vol. 140, 2020, Art. no. 110154, doi: 10.1016/j.chaos.2020.110154.

I. Cooper, A. Mondal, and C. G. Antonopoulos, “A SIR model assumption for the spread of COVID-19 in different communities,” Chaos, Solitons & Fractals, vol. 139, 2020, Art. no. 110057, doi: 10.1016/j.chaos.2020.110057.

S. Saharan and C. Tee, “A COVID-19 vaccine effectiveness model using the susceptible-exposed-infectious-recovered model,” Healthc. Anal., vol. 4, no. July, p. 100269, 2023, doi: 10.1016/j.health.2023.100269.

P. B. Borah, D. Robidas, K. Dehingia, B. J. Nath, and H. K. Sarmah, “On the Dynamics of COVID-19 Propagation with Vaccination and Optimal Control Strategies,” Brazilian J. Phys., vol. 55, no. 3, 2025, doi: 10.1007/s13538-025-01769-y.

R. C. Poonia, A. K. J. Saudagar, A. Altameem, M. Alkhathami, M. B. Khan, and M. H. A. Hasanat, “An Enhanced SEIR Model for Prediction of COVID-19 with Vaccination Effect,” Life, vol. 12, no. 5, 2022, doi: 10.3390/life12050647.

O. Diekmann, J. A. P. Heesterbeek, and M. G. Roberts, “The construction of next-generation matrices for compartmental epidemic models,” J. R. Soc. Interface, vol. 7, no. 47, pp. 873–885, 2010, doi: 10.1098/rsif.2009.0386.

J. O. Irwin, Mathematical Epidemiology, vol. 1, no. 5082. 1958. doi: 10.1136/bmj.1.5082.1287-a.

D. Uçar and E. Çelik, “Analysis of Covid 19 disease with SIR model and Taylor matrix method,” AIMS Math., vol. 7, no. 6, pp. 11188–11200, 2022, doi: 10.3934/math.2022626.

S. S. Suwardi Annas, Muh. Isbar Pratama, Muh. Rifandi, Wahidah Sanusi, “Stability analysis and numerical simulation of SEIR model for pandemic COVID-19 spread in Indonesia,” Psychiatry Res., vol. 14(4), no. January, p. 293, 2020.

R. M. N. U. Rajapaksha et al., “An extended Susceptible-Exposed-Infected-Recovered (SEIR) model with vaccination for forecasting the COVID-19 pandemic in Sri Lanka,” Sri Lanka J. Heal. Res., vol. 2, no. 1, pp. 77–95, 2022, doi: 10.4038/sljhr.v2i1.54.

D. He et al., “Evaluation of Effectiveness of Global COVID-19 Vaccination Campaign,” Emerg. Infect. Dis., vol. 28, no. 9, pp. 1873–1876, 2022, doi: 10.3201/eid2809.212226.

B. Kammegne et al., “Mathematical Modelling of the Spatial Distribution of a COVID-19 Outbreak with Vaccination Using Diffusion Equation,” Pathogens, vol. 12, no. 1, 2023, doi: 10.3390/pathogens12010088.

I. Tellez, “Modeling intervention strategies in epidemic disease outbreaks,” 2014.

B. Billah, M. L. King, R. D. Snyder, and A. B. Koehler, “Exponential smoothing model selection for forecasting,” Int. J. Forecast., vol. 22, no. 2, pp. 239–247, 2006, doi: 10.1016/j.ijforecast.2005.08.002.

O. N. Bjørnstad, K. Shea, M. Krzywinski, and N. Altman, “The SEIRS model for infectious disease dynamics,” Nat. Methods, vol. 17, no. 6, pp. 557–558, 2020, doi: 10.1038/s41592-020-0856-2.

E. Ostertagová and O. Ostertag, “Forecasting using simple exponential smoothing method,” Acta Electrotech. Inform., vol. 12, no. 3, pp. 1–6, 2013, doi: 10.2478/v10198-012-0034-2.

E. E, “Modified Holt’s Linear Trend Method Based on Particle Swarm Optimization,” COJ Robot. Artif. Intell., vol. 1, no. 3, pp. 1–4, 2020, doi: 10.31031/cojra.2020.01.000512.

E. P. Hendri and S. Fadhlia, “Times series data analysis: The Holt-Winters model for rainfall prediction In West Java,” Int. J. Appl. Math. Sci. Technol. Natl. Def., vol. 2, no. 1, pp. 1–8, 2024, doi: 10.58524/app.sci.def.v2i1.325.




DOI: https://doi.org/10.37905/euler.v13i3.34182

Refbacks

  • There are currently no refbacks.


Copyright (c) 2025 Ndaru Atmi Purnami, Luqman Nuradi Prawadika, Irvandi Gorby Pasangka, Findasari Findasari, Eka Kusumawati, Ilham Yoga Pratama, Ridho Suharis, Nadhira Hasna Maturbongs

Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.


Euler : Jurnal Ilmiah Matematika, Sains dan Teknologi has been indexed by:


 EDITORIAL OFFICE OF EULER : JURNAL ILMIAH MATEMATIKA, SAINS, DAN TEKNOLOGI

 Department of Mathematics, Faculty of Mathematics and Natural Science, Universitas Negeri Gorontalo
Jl. Prof. Dr. Ing. B. J. Habibie, Tilongkabila, Kabupaten Bone Bolango 96554, Gorontalo, Indonesia
 Email: [email protected]
 +6287777-586462 (WhatsApp Only)
 Euler : Jurnal Ilmiah Matematika, Sains dan Teknologi (p-ISSN: 2087-9393 | e-ISSN:2776-3706) by Department of Mathematics Universitas Negeri Gorontalo is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.  Powered by Public Knowledge Project OJS.